Note that the numbers in parentheses (1, 2, and so forth.) are clickable links to medically peer-reviewed studies. If someone receives ozone remedy via the rectum, they could expertise discomfort, cramping, and a feeling of needing to cross gas. People who bear ozone therapy typically expertise the Herxheimer response. This could make the individual have flu-like symptoms and cause them to feel worse within the short-term.
Side effects
The 18 chosen medical trials included 1279 sufferers (ranging from 12 to four hundred sufferers per study), of which 1185 sufferers have been adults and 94 have been children. Ozone therapy was evaluated concerning the treatment of diabetic foot ulcers, digital ulcers, chronic venous leg ulcers, atopic dermatitis, skin burns, onychomycosis, tinea pedis, cutaneous leishmaniasis, balanitis xerotica obliterans and multiple widespread warts. Only three research, addressing the remedy of cutaneous leishmaniasis, pores and skin ulcers and pores and skin burns, evidenced lack of effectiveness of ozone remedy. Mild adverse results occurred in three scientific trials, whereas severe side effects occurred in only one scientific trial, relating to skin ulcers. Therefore, ozone therapy may be instructed as an alternative or complementary treatment in some forms of dermatological situations specially affecting refractory sufferers.
However, copious volumes of research have provided proof that O3's dynamic resonance constructions facilitate physiological interactions helpful in treating a myriad of pathologies. Specifically, O3 remedy induces average oxidative stress when interacting with lipids. This interaction will increase endogenous manufacturing of antioxidants, local perfusion, and oxygen supply, in addition to enhances immune responses. We have conducted a complete review of O3 remedy, investigating its contraindications, routes and concentrations of administration, mechanisms of action, disinfectant properties in various microorganisms, and its medicinal use in different pathologies. We explore the therapeutic value of O3 in pathologies of the cardiovascular system, gastrointestinal tract, genitourinary system, central nervous system, head and neck, musculoskeletal, subcutaneous tissue, and peripheral vascular illness.
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